omnadren 250 jelfa

Prevention of stroke, systemic thromboembolism and reduced cardiovascular mortality in patients with atrial fibrillation: the parenteral use of anticoagulants should be started within 12 hours after the last dose of the drug .

Transition from parenteral anticoagulants for use of the drugomnadren 250 jelfa

The first dose of the drug PRADAKSA appointed instead of being canceled anticoagulant in the range of 0-2 hours before the next injection for a period of alternative therapy or concurrently with the termination of a continuous infusion (eg, intravenous administration of unfractionated heparin, UFH).

The transition from the use of vitamin K antagonists, to the use of the drug 

Prevention of stroke, systemic thromboembolism and reduced cardiovascular mortality in patients with atrial fibrillation:

The transition from the use of  preparation for use of vitamin K antagonists

When creatinine clearance ≥50 ml / min, the use of vitamin K antagonists is possible for 3 days, and with creatinine clearance 30-50 ml / min – 2 days prior to cancellation  drug.

cardioversion

Prevention of stroke, systemic thromboembolism and reduced cardiovascular mortality in patients with atrial fibrillation
of scheduled or emergency cardioversion does not require discontinuation of the drug.

missed dose

Prevention of venous thromboembolism in patients undergoing orthopedic surgery
is recommended to take the usual daily dose omnadren 250 jelfa at the usual time the next day. In the case of missing individual doses should not take a double dose.

Prevention of stroke, systemic thromboembolism and reduced cardiovascular mortality in patients with atrial fibrillation:
the missed dose PRADAKSA the drug can be taken in the case before receiving the next dose is 6 hours or more; if the period of less than 6 hours, the missed dose should not be accepted. In the case of missing individual doses should not take a double dose.

 

 

Side effect:

 

Side effects identified when using the drug for the prevention of VTE after orthopedic surgery and for the prevention of stroke and systemic thromboembolism in patients with atrial fibrillation.

Violations of the blood and lymphatic system:
anemia, thrombocytopenia.

Violations of the immune system:
hypersensitivity reactions including urticaria, rash and itching, bronchospasm.

Disorders of the nervous system:
intracranial bleeding.

Violations of the vessels:
hematoma, bleeding.

Violations of the respiratory, thoracic and mediastinal disorders:
epistaxis, hemoptysis.

Disorders of the gastrointestinal tract:
gastrointestinal bleeding, rectal bleeding, hemorrhoids bleeding, abdominal pain, diarrhea, dyspepsia, nausea, ulceration of the gastrointestinal mucosa, gastroezofagit, gastroesophageal reflux disease, vomiting, dysphagia.

Violations of the hepatobiliary system:
increased activity of “liver” transaminases, abnormal liver function, hyperbilirubinemia.

Changes in the skin and subcutaneous tissue disorders:
cutaneous hemorrhagic syndrome.

Musculoskeletal disorders, disorders of the connective tissue and bone:
hemarthrosis.

Changes in the kidney and urinary tract diseases:
urogenital bleeding, hematuria.

Violations of a general nature, and changes in the place of injection:
bleeding from the injection site, bleeding from the catheter site.

Damage toxicity and complications from procedures:
post-traumatic hematoma, bleeding from omnadren 250 jelfa the site of surgical approach.

For more specific side effects identified in the prevention of venous thromboembolism in patients undergoing orthopedic surgery performed:

Violations of the vessels:
bleeding from the surgical wound.

General disorders and administration site at:
spotting.

Damage Toxicity and complications of treatment posleperatsionnoy:
hematoma after the treatment of wounds, bleeding after the treatment of wounds, anemia in the postoperative period, discharge from the wound after the procedure, the secretion from the wound.

Surgical and therapeutic procedures:
the wound drainage, drainage of the wound after treatment.

 

 

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